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By all these facts, the effect upon the healthy organism of very small doses of specific substances is proved; but the sensitiveness of diseased organs is often much greater (I will only cite the great sensitiveness of the eye to light, in iritis), so that we can only wonder that any one doubts the efficacy of our remedies when exhibited in the third or sixth attenuation; with this, we do not forget that the power of reaction in diseased organs may be lessened; naturally we give them stronger doses, even down to the tincture, for individualizing, even in the dose, is one of our essential principles:

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